Publications

Publications

Publications

2026

2026

Dysregulated calcium signaling underlies hyposalivation and microbial dysbiosis in Down syndrome

Dysregulated calcium signaling underlies hyposalivation and microbial dysbiosis in Down syndrome

Ga-Yeon Son, Guilherme HS Bomfim, Fangxi Xu, Scott C Thomas, Kristen Rosenberg, Tommy Kim, Eleni Rice, Enkhnaran Budjav, Rebecca Jones, Yin-Hu Wang, Erna Mitaishvili, Stefan Feske, Drew R Jones, Edwin Rosado-Olivieri, Beverly A Rothermel, Deepak Saxena, Rodrigo S Lacruz

Cell Reports

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2025

2025

Elevated mitochondrial metabolism in Down syndrome iPSCs reduces commitment to neuroectoderm

Elevated mitochondrial metabolism in Down syndrome iPSCs reduces commitment to neuroectoderm

Malay Chaklader, Guilherme Henrique Souza Bomfim, Neil Jeju, Yingli Duan, Brian F Niemeyer, Joaquin M Espinosa, Edwin Rosado-Olivieri, Weichun Lin, Rodrigo S Lacruz, Beverly Rothermel

bioRxiv

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2024

2024

A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist

A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist

Jérémie Le Pen, Gabrielle Paniccia, Volker Kinast, Marcela Moncada-Velez, Alison W Ashbrook, Michael Bauer, H-Heinrich Hoffmann, Ana Pinharanda, Inna Ricardo-Lax, Ansgar F Stenzel, Edwin A Rosado-Olivieri, Kenneth H Dinnon III, William C Doyle, Catherine A Freije, Seon-Hui Hong, Danyel Lee, Tyler Lewy, Joseph M Luna, Avery Peace, Carltin Schmidt, William M Schneider, Roni Winkler, Elaine Z Yip, Chloe Larson, Timothy McGinn, Miriam-Rose Menezes, Lavoisier Ramos-Espiritu, Priyam Banerjee, John T Poirier, Francisco J Sanchez-Rivera, Aurelie Cobat, Qian Zhang, Jean-Laurent Casanova, Thomas S Carroll, J Fraser Glickman, Eleftherios Michailidis, Brandon Razooky, Margaret R Macdonald, Charles M Rice

PLoS Biology

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2024

2024

The emergence of human gastrulation upon in vitro attachment

The emergence of human gastrulation upon in vitro attachment

Riccardo De Santis, Eleni Rice, Gist Croft, Min Yang, Edwin A Rosado-Olivieri, Ali H Brivanlou

Stem Cell Reports

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2023

2023

Report of the assay guidance workshop on 3-dimensional tissue models for antiviral drug development

Report of the assay guidance workshop on 3-dimensional tissue models for antiviral drug development

Robert Jordan, Stephanie L Ford-Scheimer, Rodolfo M Alarcon, Anthony Atala, Jeffrey T Borenstein, Kyle R Brimacombe, Sara Cherry, Hans Clevers, Mindy I Davis, Simon GP Funnell, Lee Gehrke, Linda G Griffith, Abigail C Grossman, Thomas Hartung, Donald E Ingber, Nicole C Kleinstreuer, Calvin J Kuo, Emily M Lee, Christine L Mummery, Thames E Pickett, Sasirekha Ramani, Edwin A Rosado-Olivieri, Evi B Struble, Zhengpeng Wan, Mark S Williams, Matthew D Hall, Marc Ferrer, Sarine Markossian

The Journal of infectious diseases

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2023

2023

Organotypic human lung bud microarrays identify BMP-dependent SARS-CoV-2 infection in lung cells

Organotypic human lung bud microarrays identify BMP-dependent SARS-CoV-2 infection in lung cells

Edwin A Rosado-Olivieri, B Razooky, J Le Pen, Riccardo De Santis, D Barrows, Ziad Sabry, H-H Hoffmann, J Park, Thomas S Carroll, John T Poirier, Charles M Rice, Ali H Brivanlou

Stem Cell Reports

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2021

2021

Self-organization of human dorsal-ventral forebrain structures by light induced SHH

Self-organization of human dorsal-ventral forebrain structures by light induced SHH

Riccardo De Santis, Fred Etoc, Edwin A Rosado-Olivieri, Ali H Brivanlou

Nature Communications

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2021

2021

Synthetic by design: exploiting tissue self-organization to explore early human embryology

Synthetic by design: exploiting tissue self-organization to explore early human embryology

Edwin A Rosado-Olivieri, Ali H Brivanlou

Developmental biology

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2020

2020

Gastruloids gain muscle: somite formation in embryo-like structures

Gastruloids gain muscle: somite formation in embryo-like structures

Edwin A Rosado-Olivieri, Ali H Brivanlou

Cell Stem Cell

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2020

2020

Identification of a LIF-responsive, replication-competent subpopulation of human β cells

Identification of a LIF-responsive, replication-competent subpopulation of human β cells

Edwin A Rosado-Olivieri, Idil I Aigha, Jennifer H Kenty, Douglas A Melton

Cell Metabolism

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2019

2019

YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells

YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells

Edwin A Rosado-Olivieri, Kendall Anderson, Jennifer H Kenty, Douglas A Melton

Nature Communications

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2017

2017

A START-domain-containing protein is a novel marker of nervous system components of the sea cucumber Holothuria glaberrima

A START-domain-containing protein is a novel marker of nervous system components of the sea cucumber Holothuria glaberrima

Edwin A Rosado-Olivieri, Gibram A Ramos-Ortiz, Josué Hernández-Pasos, Carlos A Díaz-Balzac, Edwin Vázquez-Rosa, Griselle Valentín-Tirado, Irving E Vega, José E García-Arrarás

Comparative Biochemistry and Physiology

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2016

2016

Two Na+ sites control conformational change in a neurotransmitter transporter homolog

Two Na+ sites control conformational change in a neurotransmitter transporter homolog

Sotiria Tavoulari, Eleonora Margheritis, Anu Nagarajan, David C DeWitt, Yuan-Wei Zhang, Edwin Rosado, Silvia Ravera, Elizabeth Rhoades, Lucy R Forrest, Gary Rudnick

Journal of Biological Chemistry

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OUR MISSION


We chase the mysteries of human development, and turn what we learn into new ways to treat disease.


We chase the mysteries of human development, and turn what we learn into new ways to treat disease.


We chase the mysteries of human development, and turn what we learn into new ways to treat disease.

New York University

Department of Molecular Pathobiology, College of Dentistry

Department of Biomedical Engineering, Tandon School of Engineering

Email the lab